Tracing the minimum-energy path on the free-energy surface

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Tracing the minimum-energy path on the free-energy surface.

The free-energy profile of a reaction can be estimated in a molecular-dynamics approach by imposing a mechanical constraint along a reaction coordinate (RC). Many recent studies have shown that the temperature can greatly influence the path followed by the reactants. Here, we propose a practical way to construct the minimum-energy path directly on the free-energy surface at a given temperature....

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ژورنال

عنوان ژورنال: The Journal of Chemical Physics

سال: 2005

ISSN: 0021-9606,1089-7690

DOI: 10.1063/1.1948367